This week, the founding director of The Wyss Institute for Biologically Inspired Engineering at Harvard University, Dr Donald Ingber, questioned journal editors and peer reviewers about a new form of publication bias. In an opinion piece in Advanced Science entitled, “Is it Time for Reviewer 3 to Request Human Organ Chip Experiments Instead of Animal Validation Studies?,” Ingber questions why animal data is still considered the gold standard in human health research, while presenting evidence that organs-on-chips (organs chips) may better suit this purpose.